eBike vs traditional bike comparison

Hey everyone!

Been thinking a lot lately about custom builds, and it got me wondering about the fundamental differences when you're planning an eBike build versus a traditional analog bike. For those of you who've tackled both, what are the biggest considerations or compromises you've had to make? I'm particularly curious about frame material choices, component durability, and how the added weight/power changes your ideal geometry for, say, a 50-mile mixed-terrain adventure.

Looking forward to hearing your thoughts and experiences!